Psoriasis is a condition of the skin where skin cells build up and form scales on the skin along with itchy, dry patches.
It is a common skin condition that affects roughly three million people per year.
When psoriasis flares, it is very bothersome and comes with intense itchiness that burns and pains from where the patches are located.
Dermatologists have believed psoriasis to be a condition that is affected by the immune system with triggers including infections, stress, and cold temperatures.
The treatment involved in controlling psoriasis has been to remove the scales and to stop skin cells from growing quickly.
A recent article discussed a study that was conducted on patients with moderate to severe psoriasis.
The study succeeded at controlling symptoms with a new fixed-dose combination treatment of halobetasol propionate 0.01% and tazarotene 0.045% lotion as an alternative to the typical treatment.
In the study, there were several groups of patients including combination treatment, halobetasol propionate alone, tazarotene monotherapy, or vehicle in the multicenter.
- After 8 weeks of treatment, there was a 53% success from the combination group with at least a 2-point gain in Investigator’s Global Assessment of Disease Severity and a score of “clear” or “almost clear.”
From the combination therapy, patients experienced greater reduction in erythema (reddening of the skin), plaque elevation, and scaling at the lesion location.
Doctors involved in the study were not too surprised by the results because the drugs used are complimentary mechanisms of action.
The most common adverse reactions noted from the combination treatment were application site reactions, such as minor irritation.
Some skin atrophy was noted as well.
Psoriasis is one of those skin conditions that should be closely monitored by a professional dermatologist.
Ongoing treatment leads to better outcomes and determining which treatment works best for your psoriasis should be discussed with your dermatologist.
WNY Dermatology has extensive experience with managing psoriasis. Give our team a call today.